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Zoladex la este utilizat pentru tratamentul cancerului de prostată. Zoladex LA se prezintă sub formă de implant într- o o seringă preumplută, gata pentru a fi folosită de medic sau asistenta medicală. AstraZeneca UK Limited.

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Twelve patients with advanced prostatic carcinoma and relapse following previous hormone manipulation therapy were treated with Zoladex- depot every 4 weeks. Prostate cancer cells use testosterone to grow and multiply. The new formation,

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Vezi mai mult Cancerul de prostată Recurent. Costă medicamente. Cancerul de prostată recurente apare atunci când cancerul s-a întors după tratament.

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Previously, the incidence of PCa in Asian countries was relatively low, but it has been increasing dramatically in recent years. Although most of the new cases are diagnosed in early stages, a significant proportion of patients receive hormone therapy for metastatic disease or for relapse after local treatment. Thus the situation has gradually changed toward earlier and longer use of hormone therapy. The malignancy finally forms castration-resistant prostate cancer CRPC despite the lack of testicular androgen.

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Abstract Recently, adoption of novel drugs for systemic treatment of metastatic prostate cancer has led to a striking improvement of response rate and survival in both hormone-sensitive and castration-resistant disease. In most cases, prostate cancer essentially depends on androgen receptor signaling axis, even in castration-resistant setting, and hence may be targeted by second generation hormonal therapy. However, a subset of patients bears androgen-independent cancer biology with a short-term response to hormonal treatment, early and extensive visceral metastases, low PSA levels and poor outcomes. Identification and specific management of these rapidly fatal malignancies is of an unmet medical need since their classification and utilized therapeutic regimens vary significantly.

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