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Acest tip de tumori nu se găsesc numai la nivelul tractului genital. Mai rar, ele se pot găsi şi manifesta la nivelul tracturilor digestiv, respirator, urinar, vascular, sistemului cutanat, retroperitoneal.

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PCMC is more frequently found in males and it usually appears between the ages of 50 and Mendoza and Hedwig made the first contemporary description of this eyelid-located tumour. Taking into consideration the rarity of this tumour, a diagnosis of certitude is difficult to establish until further investigations are made, in order to eliminate the primary malignant tumour with visceral location with mucine production that can metastasize at cutaneous level, as for example that of breast, gastrointestinal tract, lung, kidney, ovary, pancreas, or prostate.

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Many environmental factors are recognized as carcinogenic in humans for this form of neoplasia and some of them are related to occupation. In order to illustrate these effects, we have selected several relevant cases with smoking and occupational exposure to carcinogens and their histopathological findings. We reviewed the most important research published in the field of environmental-genomic interaction in relation with the oncogenesis of BC. Three main directions have been identified and described in the article: the environmental factors involved in BC pathogenesis and evolution, the molecular mechanisms involved in cell mitosis control and xenobiotic metabolism related to the qualitative and quantitative exposure and, finally, the possible biomarkers of the tumor evolution.

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Pornind de la statistica realizată în clinica noastră şi ţinând cont de datele oferite de literatură, adesea cu rezultate divergente, încercăm în această lucrare să evaluăm oportunitatea conservării sau extirpării anexelor, din punct de vedere al rezultatelor postoperatorii. Material şi metodă A fost uterine cancer odds retrospectiv statistica clinicii de chirurgie a Spitalului Căi Ferate Craiova în perioada Au fost incluse în studiu toate cazurile la care s-a realizat histerectomia totală pentru afecţiuni benigne ale uterului.