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Radiol Oncol ; 53 3 :09 Currently, several predictive or prognostic genetic alterations have been identified and are used in clinical practice. BRAF VE mutations are rare and occur mostly in tumors located in the ascending colon in elderly female patients. BRAF is instrumental in establishing prognosis: survival is shorter by months in BRAF-mutant patients, and BRAF may be a negative prognostic factor for patients who undergo hepatic or pulmonary metastasectomy.

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Aceste exemple pot conține termeni colocviali. Recent data demonstrate that patients with KRAS wild-type metastatic colorectal cancer have a significantly higher chance to benefit from treatment with cetuximab or a combination of cetuximab and chemotherapy. Date recente demonstrează că pacienţii cu cancer colorectal metastatic şi genă KRAS de tip sălbatic au posibilităţi semnificativ mai mari de a beneficia de pe urma tratamentul cu cetuximab sau de asocierea cetuximabului cu chimioterapia. In metastatic colorectal cancer, Xeloda taken on its own has been compared with the combination of 5-FU and folinic acid in two studies involving 1, patients.

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Radu Costea Stefan Neagu Rev. Neagu', R. Methods: Our epidemiological clinical study is based on prospectivc analysis of cases of rectal cancer operated between and Survival evaluat ion was prospective cohort follow-up study.

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The benefits are certain in some cases: life years gained for those with curable disease, avoidance of morbidity, reassurance that the disease is at a very early stage, avoiding expenses of rectal cancer under 30 for advanced cancers and extra years of productivity. But screening tests also have disadvantages, so a balanced decision must be made, with the help of clinical randomized trials. In this article I will present the current methods for screening accepted for general population and particular screening reserved for persons at high risk. Although in the first case the benefit is proven, the use of these methods in practice varies largely due to lack of resources and well designed health programs.

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