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Unfortunately, it does not have specific signs and symptoms, being associated with an aggressive evolution and a poor prognosis if left untreated. Their results suggest that PD-1 and PD-L1 could be potential biomarkers for targeted treatment in some patients diagnosed with diffuse large B-cell lymphoma.

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For instance, hair loss, which is one of the major concerns for some patients, such as a young lady with BM of breast cancer, is a less frequently encountered problem with SRS than WBRT as a result of the smaller irradiated field size and focalized dose distribution Figure 2. All the aforementioned advantages of SRS are provided by utilization of multiple convergent narrow beams to deliver high dose focal irradiation in a single fraction by using multiple cobalt sources, linear accelerators or cyclotrons 37, Similar with neurosurgery, SRS alone or in combination with WBRT has been exhibited to associate with prolonged overall survival, local control and also better neurologic status in these patients compared to WBRT alone 33, However, SRS differs from neurosurgery by offering a chance of ablative treatment to those patients who are not appropriate candidates for neurosurgery due to various reasons.

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Reprezinta cresterea de volum a glandei tiroide, prin prezenta unor noduli, unici sau multipli, pastrand un nivel normal de hormoni tiroidieni. Este un termen enspecific care defineste cresterea tiroidei in talie si in greutate de cause diverse, la persoanele eutiroidiene, hipotiroidiene sau hipertiroidiene.

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Всем доброе утро, - сказала Николь, потягиваясь в постели. - Что у нас на завтрак. - Какие-то совершенно новые овощи.

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Подойди-ка сюда, принцесса, - обратился он к Никки, - поцелуй дядю Макса. - Девочка послушно последовала указаниям.

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Они оказались перед входом в кафетерий. - А не случалось ли уже неприятностей с игуанами. - спросила Николь. - Случалось, - ответил Макс.