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All rights reserved. Endocrinologie J. Larry Jameson ; trad. Drugău, Cristina trad.

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Date similare exist i n cazul gastrinoamelor i al altor PET, unde se pare c mrimea tumorii primare este un important factor de predicie n ceea ce privete dezvoltarea metastazelor hepatice, independent de alte cauze. Prezena metastazelor la nivelul ganglionilor limfatici ; profunzimea invaziei ; rata rapid de cretere ; diferite caracteristici histologice [grad de difereniere, rata mitozelor, indicii de cretere, densitatea vascularizaiei, factorul de cretere a endoteliului vascular VEGF i expresia metaloproteinazei CD10] ; necroza ; prezena citocheratinei ; niveluri crescute de fosfataz alcalin ; vrsta naintat, stadii avansate n clasificarea OMS, TNM neuroendocrine cancer facial flushing sistemele de gradare i rezultatele citometriei n flux, cum ar fi prezena aneuploidiei, sunt toi factori importani de prognostic n dezvoltarea bolii metastatice Tabelul Pentru pacienii cu tumori carcinoide, ali factori de prognostic negativ sunt reprezentai de dezvoltarea sindromului carcinoid n special dezvoltarea bolii cardiace carcinoidesexul masculin, prezena unei tumori simptomatice sau niveluri crescute ale unor markeri tumorali [acid 5-hidroxiindolacetic 5-HIIAneuropeptidul K, cromogranina A] plus prezena altor trsturi moleculare. PETurile sau gastrinoamele au fost cel mai bine studiate PET pe termen lung, prognosticul negativ este dat de sexul feminin, supraexprimarea neuroendocrine cancer facial flushing Ha-ras sau a genei p53, absena CAPITOLUL 22 Incidena exact a tumorilor carcinoide sau a PET variaz n funcie de criteriile luate n considerare, tumorile simptomatice sau toate tumorile.

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Через минуту крики прекратились. Октопаук не выпускал Макса еще десять минут, потом он ощутил, как могучие мышцы расслабились. - Что здесь происходит. - рявкнул Макс, высвободившись из объятий инопланетянина.

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