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Papillomas are the most common intraductal mass lesions of the breast. Typically present in women in their late reproductive or postmenopausal years with an average age at presentation of 48 years Clinical presentation Patients typically report a bloody or clear serosanguinous nipple discharge of fewer than six months duration.

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Persistenţa celulelor fetale în organismul matern a condus la ipoteza că acestea ar putea induce un răspuns imun de tip grefă-gazdă şi deci la posibilitatea asocierii acestui fenomen cu Aceasta este susţinută de frecvenţa crescută a afecţiunilor imune la femei şi creşterea incidenţei acestora după sarcină. Studiile iniţiale au constatat o creştere a numărului celulelor fetale în circulaţia şi la nivelul leziunilor cutanate la pacientele cu scleroză sistemică 13,42în condiţii de creştere a compatibilităţii HLA În contrast cu aceste rezultate, nu a fost identificată o asociere între microchimerismul feto-matern şi alte afecţiuni ciroza biliară primară 44lichenul plan 45 şi lupusul eritematos sistemic LES Surprinzător, celulele fetale apar în ţesuturile materne în cazurile severe de LES, iar această prezenţă este proporţională cu severitatea afecţiunii Astfel, se presupune că celulele fetale nu declanşează afecţiunile autoimune, ci sunt recrutate de ţesuturile materne afectate, dacă leziunea tisulară atinge un anumit prag

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Breast cancer is a malignant tumor that starts in the cells of the breast. A malignant tumor is a group of cancer cells that can grow into invade surrounding tissues or spread metastasize to distant areas of the body.

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