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It has been recently demonstrated that the use of metformin as an insulin sensitizer reduces incidence, progression and even mortality through cancer Evans JM et al. A significant number of studies mention the beneficial effect that metformin has on the treatment and prognosis of certain neoplastic localizations mammary, pancreas, colorectal, hepaticmost frequently by interfering with cell cycle regulation. Thus, the study of the effects of oral anti-diabetic drugs is worth being continued, as they can bring multiple benefits to administered oncological treatments. Recent, s-a demonstrat că utilizarea metforminului ca agent de sensibilizare la insulină reduce incidența, progresia și chiar mortalitatea prin cancer Evans JM et al.

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Received Mar 9; Accepted Apr 8. Copyright © Chi-Ming Lee et al.

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