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Dar exista anumiti factori de risc care cresc riscul de a face aceasta boala. Factori de risc Primul factor de risc care creste riscul de a dezvolta acest tip de cancer este varsta.

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Functia acestor gene poate fi perturbata de deletii, insertii sau rearanjamente genomice mari. O mutatie care inactiveaza gena MMR duce la acumularea de mutatii celulare si creste foarte mult probabilitatea de transformare maligna.

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The benefits are certain in some cases: life years gained for those with curable disease, avoidance of morbidity, reassurance that the disease is at a very early stage, avoiding expenses of treatment for advanced cancers and extra years of productivity. But screening tests also have disadvantages, so a balanced decision must be made, with the help of clinical randomized trials. In this article I will present the current methods for screening accepted for general population and particular screening reserved for persons at high risk. Although in the first case the benefit is proven, the use of these methods in practice varies largely due to lack of resources and well designed health programs.

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GHID din 4 decembrie privind cancerul de endometru Anexa nr. Metodologie de elaborare3. Etapele procesului de elaborare3.

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TR Microsatellite instability MSI Instabilitatea microsatelitară MSI este o afecțiune care apare pe ADN-ul celulelor specifice cum ar fi celulele canceroase unde numărul de microsateliți repetiții scurte ale secvențelor ADN din aceste celule este diferit de repetările care au existat în ADN atunci când a fost moștenit. Această instabilitate este cauzată de funcționarea defectuoasă a mecanismului de reparare mecanismul de reparare a endometrial cancer diagnostic tests de replicare ADN, MMR a erorilor în timpul replicării ADN-ului.

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