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PMS2 TP53 APC — gena care codifica pentru o proteina cu rol critic in diferite procese celulare, actionand ca un supresor al cresterii tumorale. AXIN2 — gena care codifica pentru o proteina implicata in calea de semnalizare Wnt cu rol in diferite procese celulare inclusiv in cele de reparare a leziunilor ADN. Mutatii la nivelul genei AXIN2 determina aparitia carcinomului colonic si al sindromului care asociaza Oligodontia si Cancerul colorectal BAP1 — gena ce codifica pentru o proteina numita ubiquitin — carboxi terminal hidrolaza care actioneaza prin indepartarea moleculelor de ubiquitina de pe alte protein, ducand colorectal cancer treatment guidelines activarea acestora.

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Alte traduceri Recommended dose modifications for Thalidomide Celgene related neuropathy in first line treatment of multiple myeloma. Modificări recomandate ale dozei pentru neuropatie asociată cu Thalidomide Celgene în tratamentul de primă linie al mielomului multiplu. In this randomised, open label, controlled clinical trial, chemotherapy oxaliplatin or irinotecan and bevacizumab were given with and without panitumumab in the first line treatment of patients with metastatic colorectal cancer.

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